About Lumega-Z

Ingredients | Absorption | Vision And Nutrition | Contrast Sensitivity | Carotenoids

The Only Vision-Specific Medical Food

Lumega-Z has been used clinically since 2012. This unique formula has been taken by more than 2000 patients. Typical symptoms of these patients include poor night vision, higher sensitivity to glare and overall reduction in vision for everyday activities, like driving or playing golf.

Studies show that Lumega-Z is more easily absorbed than off-the-shelf supplements, getting more of these important nutrients into the body. Studies also show that Lumega-Z boosts the macular pigment, a thin layer of protective tissue that rests right in front of the macula. These videos are comments from real patients who have been treated with Lumega-Z and whose vision has stabilized or improved.

Listen To What Patients Say

Why Is Lumega-Z Special?

Lumega-Z is a Medical Food designed specifically for eye nutrition to restore and maintain the macular pigment. It is the only product that offers all three critical eye carotenoids – lutein, zeaxanthin and mesozeaxanthin – and a full complement of anti-inflammatory and antioxidant ingredients. Lumega-Z is a tasty, easy-to-drink liquid that helps to get the nutrients straight to your eyes. The liquid form ensures high levels of absorption of the powerful carotenoids and other nutrients.

Dr Sponsel Explains Why Lumega-Z is so Special?

Lumega-Z Is An Easily Absorbed Liquid!

Lumega-Z is provided in a micronized liquid form which makes it much easier to digest and to get the three essential carotenoids, anti-inflammatory ingredients and anti-oxidative components into the bloodstream and into the eye. The liquid formula ensures a very high level of absorption.

About Lumega-Z

Dr Stephenson Explains Why A Liquid Formula Is Better For Your Eyes!

Dr Sponsel Explains Why Lumega-Z is so Special?

Lumega-Z Ingredients

What Is In Lumega-Z?

Lumega Z includes the three macular carotenoids – lutein, zeaxanthin and meso-zeaxanthin – and a potent variety of other ingredients, including:

Vitamin CZincSeleniumVitamin D3
Vitamin ECopperThiaminManganese
RiboflavinChromiumVitamin B3Molybdenum
Vitamin B6LuteinFolateMeso-zeaxanthin
Vitamin B12ZeaxanthinBiotinLycopene
Pantothenic AcidAstaxanthinCalciumNAC
QuercetinProprietary Ocular Antioxidant Blend

Lumega-Z is accompanied by a separate bottle of Omega Boost, which provides essential Omega fatty acids, including DHA and EPA.

Ingredients Table

The full ingredients tables for Lumega-Z and Omega Boost shown below.

About Lumega-Z

Guardion Health Sciences, the maker of Lumega-Z, cannot guarantee the same results as these patients for vision improvement or any vision benefit with treatment.


Absorption Of Lumega-Z Versus Nutritional Supplements

About Lumega-Z

Lumega-Z is packed with carotenoids that make up the macular pigment, as well as a complement of other vitamins, minerals and nutrients that are critical to ocular and overall health. Because of this wide range of nutrients in the formula, Lumega-Z can often replace your daily multivitamin and other supplements.

While some of the other vitamins and supplements you currently take may come in a gel capsule, tablet or pill form, Lumega-Z is liquid. Liquid has numerous advantages over gel capsules or pills.

Liquids Are Packed With More Powerful Nutrients

Liquids allow a higher concentration and a more synergistic combination of ingredients. The manufacturers can combine complex combinations of ingredients like herbal ingredients, foods and vitamins into liquids easier than in a chewable or gel capsule.

Easily And Efficiently Digested And Absorbed

Lumega-Z’s liquid lipid-based delivery system delivers nutrients to the body quicker than pills or capsules can. Gel capsules, pills or tablets must be swallowed and digested to be absorbed. The body has to break these supplements down in order to extract the medicinal properties of the nutrients. This can take hours. But the body doesn’t have to break down liquids like Lumega-Z. There are no casings or fillers for the body to process. Lumega-Z is much easier for the body to digest and absorb. Lumega-Z has higher bioavailability than gel capsules or pills — meaning a greater percentage of the nutrients are absorbed by the body’s circulation. The body doesn’t utilize nearly as much of the nutrients in capsules, pills or tablets.

Research backs up these claims. There have been many reports demonstrating that products similar to Lumega-Z in formula but in a pill or capsule form have poor absorption rates.

About Lumega-Z

Efficacy of Commercially Available Nutritional Supplements: Analysis of Serum Uptake, Macular Pigment Optical Density and Visual Functional Response. R Bone, PG Davey, B Roman and D Evans. Nutrients, 12, 1321, 2020.

Evaluation of Visual Functional Changes in Eyes with Drusen using the Micronized Lipid-Based Carotenoid Liquid Supplementation and AREDS-2 Formula. D Lem, T Henderson, R Weis, S Amonoo-Monney, D. Evans, P Davey. ARVO Poster, 2019.

This study evaluated the visual function benefits of Lumega Z Versus AREDS 2 formula in patients with drusen who were at risk for vision loss from AMD. The data showed a significant improvement in contrast sensitivity for the Lumega Z group, but not for AREDS, after 6 months of treatment. A third, untreated, control group also showed no change in visual function.

Efficacy of Commercially Available Nutritional Supplements: Analysis of Serum Uptake, Macular Pigment Optical Density and Visual Functional Response. R Bone, PG Davey, B Roman and D Evans. Nutrients, 12, 1321, 2020.

This study compared the bioavailability, as measured by blood absorption levels, of macular carotenoids provided by Lumega-Z micronized liquid formula versus AREDS 2 gel caps. Data showed that after 12 weeks of treatment, Lumega-Z provided 4 times the level of macular carotenoids in the blood assays, even though the concentration of carotenoids in the formula is only 2.3 times higher than AREDS 2. Lumega-Z also provided higher levels of MPOD in subjects taking this formula, while no changes were noted for the AREDS 2 treated subjects.

Easy To Consume

Lots of people, particularly the elderly, have trouble swallowing tablets or capsules. Medications or supplements in pill or capsule form can get stuck in the throat or cause gagging. Liquids like Lumega-Z are very easy to drink. Lumega-Z can be mixed with a tasty beverage like juice or water. Also, the product is safe for people with sensitivities or allergies, as it is free from sugar, gluten, dairy or artificial colors.

Higher Concentration Of Nutrients

Liquids like Lumega-Z are able to pack in a higher concentration of nutrients than gel caps or tablets. You would need to take dozens of tablets or gel caps to equal the nutrients in a single dose of Lumega-Z.

Vision And Nutrition

Medical Foods

About Lumega-Z

As we age, our bodies have specific nutritional requirements to maintain healthy vision. Unfortunately, the typical diet does not include enough of the specific nutrients to keep our protective macular pigment at its best. The good news, however, is that making dietary changes to include eye-friendly nutrients in your diet can help preserve eye health for many years to come.

Guardion Health Sciences combines cutting-edge technology and highly specialized Medical Foods to help you maintain good eye health, particularly the health of the macular pigment. Continue reading to learn more about how diet affects your eye health.

The Role Of Diet In Eye Health

The impact that diet has on overall health is well-documented. Eating a diet high in saturated fat and sugar increases one’s risk of certain health conditions. Conversely, a diet rich in vitamins and minerals like fruits and vegetables can minimize the risk of developing these conditions and other health problems. 

About Lumega-Z

Carotenoids Are Key To Eye Health

Foods high in carotenoids protect the eyes in two ways. First, carotenoids form the macular pigment which lies directly in front of central vision, called the macula, and absorbs ultraviolet light before it strikes the retina. Second, carotenoids provide significant anti-oxidant activity which slows or stops free radical damage to the macula and retina. Carotenoids are pigments present in plants and algae, and are responsible for the vibrant red, orange and green color in vegetables and fruits. There are three types of carotenoids that make up the macular pigment: lutein, zeaxanthin and meso-zeaxanthin. It is difficult in the western diet to obtain sufficient levels of the three macular carotenoids. Supplementation of these essential carotenoids is essential to maintain a healthy macular protective pigment.

Contrast Sensitivity

Contrast Sensitivity And Eye Health

Contrast sensitivity is a very accurate and sensitive measure of eye health, before other tests. This test can also measure improvements in vision after treatment with Lumega-Z. Improvements in contrast sensitivity can occur as early as 2 to 3 months after patients start taking Lumega-Z. The Big E chart, typically used by eye care professionals to test your vision, cannot measure these improvements until many months later, if at all.

Below is an example of the Big E Chart, formally known as The Snellen Chart. The chart tests only black-on-white letters.

About Lumega-Z

While the Big E Chart measures only black on white, contrast sensitivity measures how well you can see shades of gray in the real world. Below are two pictures of the same real-world scene, one in high contrast and one in low contrast. Many people can read the black on white letters of the Big E Chart, but have trouble seeing the little girl in the street under low contrast.

About Lumega-Z

Contrast sensitivity is a very accurate and sensitive measure of eye health before other tests. This test can also measure improvements in vision after treatment with Lumega-Z. Improvements in contrast sensitivity can occur as early as 2 to 3 months after patients start taking Lumega-Z. The Big E chart cannot measure these improvements until many months later, if at all.

Contrast Sensitivity And Carotenoids

The secret to Lumega-Z’s ability to improve contrast sensitivity lies in its special and unique formula. Lumega-Z is the only Medical Food that contains all three macular carotenoids, as well as a full complement of antioxidant and anti-inflammatory ingredients. Further, Lumega-Z is the only Medical Food designed directly to replenish and restore the macular pigment, the area in the center part of your eye responsible for protecting and enhancing your central vision. Research shows that patients with reduced macular pigment often have reduced contrast sensitivity. After taking Lumega-Z, many patients report that they can see better in the real world under low-contrast conditions like driving at night, finding items in a darkened garage or stepping over a curb at dusk.

Research Shows Carotenoids Improve Contrast Sensitivity

This case reports shows a patient whose contrast sensitivity improved after taking the vision-specific Medical Food, Lumega-Z. The contrast sensitivity is low, below the normal range, and the curve shifts up into the normal range – the solid blue area.

About Lumega-Z

How Do You Measure Contrast Sensitivity?

The most scientific and accurate way to measure contrast sensitivity is to use a type of bar pattern, called a sine-wave grating, in a test that uses a calibrated light source which holds testing light level extremely consistent. During the test, different size gratings are presented to the patient at different levels of contrast. The patient simply says when they can or cannot see the gratings.

Some eye doctors use lower quality types of contrast tests that present gray letters instead of the scientifically-proven grating bar patterns. These letter tests are less sensitive and the FDA does not recommend letter contrast tests for use in their clinical trials.

About Lumega-Z

Results For Study Comparing Lumega-Z To PreserVision

A study found significant improvements in visual function as measured by contrast sensitivity for patients taking Lumega-Z. Patients taking AREDS-2 showed no improvements in vision.

This graph shows the percent changes in contrast sensitivity, as measured by the CSV-1000, at baseline and after 3 and 6 months of treatment, for the control group (no treatment), the PreserVision Group and the Lumega-Z Group. Lumega-Z provided highly significant improvements in contrast sensitivity.

About Lumega-Z

This graph shows the percent changes in contrast sensitivity, as measured by the CSV-1000, at baseline and after 3 and 6 months, for the control group (no supplementation), the PreserVision Group and the Lumega-Z Group. Lumega-Z provided for highly significant improvements in contrast sensitivity.

Individual Contrast Sensitivity Results Following Lumega-Z Treatment

The graph below shows the clinical data for a 70 year-old white female. The “Before” curve represents the patient’s contrast sensitivity before and the “After” curve shows the patient’s response after 6 months of taking Lumega-Z. Note that the patient shifted up dramatically in contrast sensitivity across the full range of the curve, at all spatial frequencies. The patient had 20/20 acuity before and after 6 months of treatment, which means that standard acuity testing could not have detected this difference. It is encouraging to find patients showing dramatic improvements in their vision after taking Lumega-Z (these results cannot be guaranteed for all patients).

About Lumega-Z

You Should Have Your Contrast Sensitivity Tested Regularly

Contrast sensitivity is a very important measure of vision. You should have it tested regularly. In the United States, this test is not covered by insurance, although it is in many other countries. Make sure you ask for a test that uses the special scientifically proven gratings, as shown in the examples above, and one that ensures the test is conducted under conditions where the test lighting is standardized to the level recommended by the FDA and National Academy of Sciences.


Carotenoids And Your Vision

The central part of the eye has a protective pigment layer that is very important to the health of your eyes. This layer is made up of three critical carotenoids: lutein, zeaxanthin and meso-zeaxanthin. These carotenoids are called the macular pigments. Carotenoids are organic pigments that exist naturally in brightly colored and leafy plants, such as in spinach and carrots, and in some animal products like egg yolks.

Carotenoids Protect Your Eye Health In Two Ways

The three carotenoids that make up the macular pigments protect your eyes in two ways. First, they absorb the damaging UV rays from the sun. Your eye doctor has probably told you to wear sunglasses to protect your eyes from the sun. The macular pigments are like sunglasses inside the eye; they absorb the harmful rays before the UV rays can damage the central part of your vision.

About Lumega-Z

Second, the carotenoids offer significant anti-oxidant protection for the central part of the eye and throughout the retina. The retina is the most active area of the body for metabolism. Because of all of the metabolic activity, the retina produces significant amounts of metabolic waste. Powerful anti-oxidants are needed to clean up this waste and ensure that they do not collect in the back of the eye. The macular pigment is responsible for cleaning up this metabolic waste, particularly around the most important central part of your vision. A healthy macular pigment means that these metabolic waste elements do not build up and damage the eye. It is impossible to restore and maintain the macular pigment from your diet without proper supplementation.

What Is A Depleted Macular Pigment?

When the body does not get enough carotenoids, the macular pigments can become depleted. This depletion then leads to less protection for the eye from UV radiation and less antioxidant activity to protect the eye. 

How Do I Build Up My Macular Pigment?

In order to keep your macular pigment from becoming depleted, you have to have sufficient macular carotenoids in your body, specifically lutein, zeaxanthin and meso-zeaxanthin. Getting enough of these ingredients has become difficult for three reasons. First, our meals do not have the level of the carotenoids that they used to. It is impossible to eat and absorb enough carotenoids in our food sources to fully support the macular pigment. In fact, the average Western diet contains fewer than 3 mg of the macular pigments per day, yet 20 mg a day are needed to protect macular health.

About Lumega-Z

Second, our bodies change as we age. Even if there are a lot of carotenoids in our food sources, older adults cannot absorb enough to fully support the health of macular pigment. Third and most importantly, the most important carotenoid, meso-zeaxanthin, is not found commonly in nature. This very important carotenoid has to be converted inside the eye from lutein. But, as we get older, we lose the ability to complete this conversion process.

What this means is that to fully support the health of the macular pigment and the overall retina, nutritional supplements, that contain all three carotenoids and a combination of anti-inflammatory and anti-oxidant ingredients, are essential. Further, because the body loses its ability to convert meso-zeaxanthin from lutein, direct supplementation of meso-zeaxanthin is the best option to ensure sufficient levels in the eye. That is, simply taking lutein or zeaxanthin will not guarantee a sufficient supply of meso-zeaxanthin; it has to be taken in a formula.

How Does Lumega-Z Help My Macular Pigment?

Lumega-Z is a Medical Food that contains all three macular pigments. It also contains a full dose of anti-inflammatory and anti-oxidant ingredients in order to support retinal health. This formula is in a micronized liquid form which ensures high absorption of the carotenoids and other ingredients. Putting all of these ingredients together in a liquid form makes it easy to build up your macular pigments and ensure retinal health. In fact, research shows that Lumega-Z has increased macular pigment density by up to 30% in patients, after only 3 to 6 months of treatment.

Lumega-Z Is A Medical Food

Lumega-Z is the only vision-specific Medical Food. A Medical Food is defined by the FDA as a product which is formulated to be taken under medical supervision and which is intended for specific dietary management of a disease or condition. Lumega-Z has been specifically designed to restore and maintain a depleted macula pigment.

About Lumega-Z